Primary Antibody Matched Pairs
ABclonal Technology CNDP2 Rabbit pAb
CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).
ABclonal Technology STX2 Rabbit pAb
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Medchemexpress LLC LOX-1/OLR1 Rat HEK 100ug
The LOX-1/OLR1 protein plays an important role as a receptor that recognizes internalizes and degrades oxidatively modified low-density lipoprotein (oxLDL) a marker of atherosclerosis in vascular endothelial cells OxLDL induces endothelial dysfunction triggering pro-inflammatory responses oxidative conditions and apoptosis LOX-1/OLR1 Protein Rat (HEK293 His) is the recombinant rat-derived LOX-1/OLR1 protein expressed by HEK293 with N-His labeled tag
ABclonal Technology MDK Rabbit pAb
This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Human SerpinA1 ELISA Pair Set 15PP (Sino Biological)
Each vial contains 26 ng of recombinant SERPINA1. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 2000 pg/mL is recommended.
Influenza B NP ELISA Pair Set 5PP (Sino Biological)
Each vial contains 85 ng of recombinant Influenza B (B/Washington/02/2019) Nucleoprotein. Reconstitute with 1 mL dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 2500 pg/mL is recommended.
ABclonal Technology NUP98 Rabbit pAb
This gene belongs to the nucleoporin family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to produce 98 kDa and 96 kDa nucleoporins. The 98 kDa nucleoporin, containing a Gly-Leu-Phe-Gly (GLGF) repeat, is involved in nuclear import, export, mitotic progression, and gene expression regulation. The 96 kDa nucleoporin is a scaffold component of the nuclear pore complex (NPC). Proteolytic cleavage is essential for targeting these proteins to the NPC. Translocations of this gene with other genes have been observed in leukemias, resulting in chimeras with the GLGF domain fused to the partner genes C-terminus. Alternative splicing generates multiple transcript variants, including those lacking the 96 kDa nucleoporin region and those processed proteolytically.
Genscript Corporation Nectin-1/PVRL1/CD111Biotin
Nectins are a small family of Ca -independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that organize intercellular junctions They are highly homologous to the human receptor for poliovirus and as such have been alternately named poliovirus receptor-related proteins Nectin-1 promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers Heterophilic interactions have been detected between Nectin-1 and Nectin-3 and between Nectin-1 and Nectin-4 Has some neurite outgrowth-promoting activity
Genscript Corporation MSLN/Mesothelin 296-598 M593
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF) Although it has been proposed that mesothelin may be involved in cell adhesion its biological function is not known A knockout mouse line that lacks mesothelin reproduces and develops normally
Medchemexpress LLC CD70 Rat HEK293 H 50ug
CD70 is the ligand of CD27 in activated T and B lymphocytes is an important cytokine in CD70-CD27 pathway involving with the generation and maintenance of T cell immunity[1] CD70 is a surface antigen also shows antiviral activity and regulates viability of tumor cells and regulatory T cells[2][3] As for CD70 protein in rat contains TNF 2 domain (57-188 a a) and transmembrane helix belonging to the tumor necrosis factor (TNF) family CD70 Protein Rat (HEK293 His) is 150 amino acids in length (Q46-P195) and is expressed in the HEK293 cells with N terminal His-tag
Biotium RAD51 (Prognostic and Response to Chemotherapy Marker)(RAD51/2701), CF594 conjugate, 0.1mg/mL
RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancies. RAD51 overexpression correlates with histological grading of the tumor in invasive ductal mammary carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightnes
Biotium GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), CF740 conjugate, 0.1mg/mL
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (ÃŽ³-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other label
Biotium Prostate Specific Acid Phosphatase (PSAP) (ACPP/1339), CF568 conjugate, 0.1mg/mL
This antibody recognizes a protein of 52 kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium TPO (Thyroid Peroxidase) (Thyroid Marker)(TPO/1921), CF740 conjugate, 0.1mg/mL
Thyroperoxidase (TPO) is a 933 amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluores
ABclonal Technology PSAP
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland An alternatively spliced transcript variant encoding a longer isoform has been found for this gene This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway